高 雅
一、個人信息
姓名：高 雅
職稱：副教授
專業：原子與分子物理
學歷層次：博士研究生
辦公室地點：實訓樓2208
辦公電話：021-67791039
電子郵箱：gaoya@sues.edu.cn
研究方向：計算生物物理；
熒光探針機製與成像理論機製；
計算光學光電材料等🚵🏿♀️；
個人主頁：http://faculty.sues.edu.cn/_s3486/main.psp
二、教育經歷
2014.06 畢業於華東師範大學原子與分子物理專業獲博士學位
三、工作經歷
2018.09-2019.09 美國理海大學生命科學系博士後
2017.10-2021.09 華東師範大學化學與分子工程EON4博士後
2014.09-至今 EON体育4开户講師，副教授
四🛡、代表性論著 (入職以來一作或通訊)
15. X. Fang, Y. Gao*, C. Wang, H. Chen, T. Zhu*, Exploring the selective mechanism of inhibitors towards different subtypes of class I PI3K, Chem. Phys. Lett.,786, 139174, 2022
14. N. Li, Y. Gao*, F. Qiu*, T. Zhu*, Benchmark Force Fields for the Molecular Dynamic Simulation of G-Quadruplexes, Molecules, 26, 5379, 2021
13. Y. Gao, J. Lee, I. P. S. Smith, H. Lee, S. Kim, Y. Qi, J. B. Klauda, G. Widmalm, S. Khalid, W. Im*, CHARMM-GUI Supports Hydrogen Mass Repartitioning and Different Protonation States of Phosphates in Lipopolysaccharides, J. Chem. Inf. Model., 61, 831, 2021
12. Y. Gao, J. Lee, G. Widmalm*, W. Im*, Modeling and simulation of bacterial outer membranes with lipopolysaccharides and enterobacterial common antigen, J. Phys. Chem. B, 124, 5948, 2020
11. Y. Gao, J. Lee, G. Widmalm*, W. Im*, Preferred conformations of lipooligosaccharides and oligosaccharides of Moraxella catarrhalis, Glycobiology, 30, 86, 2020
10. Y. Zhang, Y. Qu*, J. Wu, Y. Rui, Y. Gao*, Y. Wu*, Naphthalimide end-capping molecular rotors with different donor cores: Tuning emission in wide gamut and cell imaging, Dyes Pigments, 179, 108431, 2020
9. Z. Gao, J. Bao, S. Shi, X. Zhang, Y. Gao*, T. Zhu*, Effect of mutations on drug resistance of smoothened receptor toward inhibitors probed by molecular modeling, Chem. Phys. Lett.,741, 137126, 2020
8. B. Wang, Y. Qi, Y. Gao*, J. Z. H. Zhang*, A method for efficient calculation of thermal stability of proteins upon point mutations, Phys. Chem. Chem. Phys., 22, 8461, 2020
7. Y. Gao, T. Zhu*, J. Z. Chen*, Exploring drug-resistant mechanisms of I84V mutation in HIV-1 protease toward different inhibitors by thermodynamics integration and solvated interaction energy method, Chem. Phys. Lett.,706, 400, 2018
6. Y. Gao, T. Zhu*, C. M. Zhang, J. Z. H. Zhang, Y. Mei*, Comparison of the unfolding and. oligomerization of human prion protein under acidic and neutral environments by molecular dynamics simulations, Chem. Phys. Lett., 706, 594, 2018
5. Y. Gao*, C. M. Zhang, T. Zhu*, A test of AMBER force fields in predicting the secondary structure of alpha-Helical and beta-hairpin peptides, Chem. Phys. Lett., 679, 112, 2017
4. Y. Gao*, C. M. Zhang, J. Z. H. Zhang, Y. Mei*, Evaluation of the coupled two-dimensional main chain torsional potential in modeling intrinsically disordered proteins, J. Chem. Inf. Model., 57, 267, 2017
3. Y. Gao, Y. Mei, J. Z. H. Zhang, Treatment of hydrogen bonds in protein simulations, Advanced Materials for Renewable Hydrogen Production, Storageand Utilization, InTech, ISBN 978-953-51-2219-7, 2015
2. Y. Gao, Y. X. Li, L. R. Mou, B. B. Lin, J. Z. H. Zhang, Y. Mei, Correct folding of an alpha-helix and a beta-hairpin using a polarized 2D torsional potential, Sci. Rep.,5, 10359, 2015
1. Y. Gao, Y. X. Li, L. R. Mou, J. Z. H. Zhang, Y. Mei, Coupled two-dimensional main-chain torsional potential for protein dynamics II: performance and validation, J. Phys. Chem. B, 119, 4188, 2015
五🌲、代表性科研項目
1. 國家自然科學基金青年項目, 21503132, 主持.
2. 中國博士後科學基金面上資助👨🏿🦱，2018M632058, 主持.
3. 上海市人才計劃“晨光計劃”, 15CG59, 主持.
4. EON体育4平台人才計劃“展翅計劃”, 主持.
六🧧、主要榮譽獎勵
2017 EON体育4平台優秀教育工作者
七、主要學術組織社會兼職
Chemical Biology & Drug Design, Chinese Journal of Chemical Physics, Current Alzheimer Research等期刊審稿人
